HVEM/U2OS Cell
CBP74178
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產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
| I. Background | |
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皰疹病毒進(jìn)入介質(zhì)（HVEM），也稱為腫瘤壞死因子受體超家族成員 14 （TNFRSF14），是 TNF 受體（腫瘤壞死因子）超家族的人細(xì)胞表面受體。HVEM 在多種 免疫細(xì)胞中表達(dá)，包括 T 細(xì)胞、B 細(xì)胞、自然殺傷細(xì)胞、樹(shù)突狀細(xì)胞和內(nèi)皮細(xì)胞。它還通 過(guò)在黑色素瘤細(xì)胞上的頻繁表達(dá)參與腫瘤的免疫逃避。 |
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| II. Introduction | |
| Expressed gene: | HVEM |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | Mccoy's5A+10%FBS+2 μg/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
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Figure 1. Recombinant HVEM/U2OS Cell constitutively expressing HVEM. |
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Figure 2. Inhibtion of HVEM Induced SHP2 Recruitment In BTLA SHP2 Reporter Cell (C11) By Icatolimab with HVEM U2OS Cell (C7). |
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